What is Vitamin B6 deficiency?

Vitamin B6 deficiency is uncommon and is usually associated with low concentrations of other B-complex vitamins, such as vitamin B12 and folic acid. A mild deficiency may have no symptoms, but a more severe or prolonged deficiency can affect immunity and skin health. 

Common vitamin B6 deficiency symptoms:

  • Anemia
  • Itchy rash
  • Scaly skin on lips
  • Cracks at the corners of mouth
  • Swollen tongue
  • Depression
  • Confusion
  • Other skin conditions
  • Weak immune system
  • Chronic inflammation
  • Irritability
  • Extremely sensitive hearing in infants
  • Seizures in infants

What causes a vitamin B6 deficiency?

  • Impaired renal function (end-stage renal diseases or chronic renal insufficiency)
  • Kidney disease
  • Autoimmune disorders
  • Alcohol dependency
  • Rheumatoid arthritis
  • Celiac disease
  • Ulcerative colitis
  • Crohn’s disease

Further reading: Harvard School of Public Health, National Institutes of Health (1),(2)